Annals of The Japanese Respiratory Society:A case of Hamman’s syndrome that presented with chest pain that developed after administration of SGLT2 inhibitors

Vol.13 No.1 Table of Contents

Abstract

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Article in Japanese

Case Report

A case of Hamman’s syndrome that presented with chest pain that developed after administration of SGLT2 inhibitors

Yoshinobu Nagano^a Manato Taguchi^a Ryusei Nakagawa^b Mao Sasamoto^a Takeshi Kawakami^a Kyoko Kondo^a

^aDepartment of Respiratory Medicine, Kobari General Hospital
^bDepartment of Respiratory Medicine, Ibaraki Seinan Medical Center Hospital

ABSTRACT

The patient was a 16-year-old man who had visited another hospital with a chief complaint of vomiting. He was diagnosed with type 2 diabetes and prescribed tofogliflozin.
Six days later, he became aware of chest pain and difficulty breathing and called for an ambulance. As a result of close examination, pneumomediastinum and diabetic ketoacidosis were detected, so he was diagnosed with Hamman’s syndrome and hospitalized. He required tracheal intubation and dialysis management but was discharged after improvement following an infusion and insulin treatment.
Only one case of Hamman’s syndrome involving SGLT2 inhibitors has been reported; we therefore present this case because we consider it to be valuable.

KEYWORDS

Pneumomediastinum Diabetic ketoacidosis (DKA) Hamman’s syndrome Tofogliflozin

Received 27 Apr 2023 ／ Accepted 10 Oct 2023

AJRS, 13(1): 39-43, 2024

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