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Article in Japanese
Abstract
Case Report
A case of pneumoconiosis after exposure to titan dioxide powder
Taisaku Koyanagi Takumi Kishimoto
Department of Internal Medicine, Okayama Rosai Hospital
ABSTRACT
We report a case of pneumoconiosis after exposure to titan dioxide powder for more than 20 years. Chest X-ray showed ground-glass opacities in all the lung fields, and high-resolution computed tomography (HRCT) showed peripheral centrilobular blurred nodular shadows. Titan dioxide was confirmed on the specimen obtained via bronchoalveolar lavage and transbronchial biopsy. Titan dioxide was deposited mainly around the pulmonary artery and peribronchiolar area. Furthermore, mediastinal and abdominal lymph node swelling was observed at high attenuation. HRCT showed mild fibrosis in the left inferior region, which was verified via biopsy. To our knowledge, this is the first case of pneumoconiosis with titan deposition in the peribronchial area, mediastinal and abdominal lymph node swelling and mild fibrosis of the lungs after long-term inhalation of titan dioxide powder.
KEYWORDS
Titanium oxide Packing Pneumoconiosis Alveolar macrophage Centrilobular dust deposition
Received 29 May 2023 ／ Accepted 23 Aug 2023
AJRS, 12(6): 329-333, 2023
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