Annals of The Japanese Respiratory Society:Severe pneumonia caused by <i>Legionella pneumophila</i> successfully treated with endotoxin adsorption and nitric oxide inhalation therapy

Abstract

Article in Japanese

Case Report

Severe pneumonia caused by Legionella pneumophila successfully treated with endotoxin adsorption and nitric oxide inhalation therapy

Tomoko Iriyama^a Masafumi Yamaguchi^a Tsukasa Nakanishi^b Yoko Tsunoda^a Keiko Narumiya^a Yasutaka Nakano^a

^aDivision of Respiratory Medicine, Department of Internal Medicine, Shiga University of Medical Science
^bDivision of Respiratory Medicine, Shiga General Hospital

ABSTRACT

A 67-year-old man presenting with fever and cough was diagnosed with pneumonia caused by Legionella pneumophila, based on a combination of right-sided infiltrative shadows on chest radiography and a positive test for the Legionella urinary antigen. The patient’s condition rapidly deteriorated despite treatment with antibiotics, and he was transferred to our hospital. Although he had to be immediately intubated due to severe respiratory failure and septic shock on admission, he recovered completely after intensive treatment that included endotoxin adsorption with polymyxin B immobilized fiber column direct hemoperfusion and nitric oxide inhalation therapy. These intensive therapies could improve outcomes for patients with severe pneumonia caused by L. pneumophila.

KEYWORDS

Legionella pneumonia Endotoxin adsorption Nitric oxide inhalation

Received 26 Apr 2023 ／ Accepted 12 Jun 2023

AJRS, 12(5): 288-292, 2023

Search for	AJRS(after 2012) JJRS(before 2011) Both of which
Year	equal after before
Volume	equal after before	Number	equal after before
Title		Author
Abstract		Keywords

Content

Abstract

Case Report

ABSTRACT

KEYWORDS