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Article in Japanese
Abstract
Case Report
A case of Stage IV G-CSF producing lung cancer successfully treated with surgery and combined immunotherapy
Eiji Sugimotoa Atsushi Nagaia Haruka Yamamotoa So Uedaa Miyu Hiroseb Osamu Yamaguchia
aDepartment of Cardiology, Pulmonology, Hypertension & Nephrology, Ehime University Graduate School of Medicine
bDepartment of Respiratory Medicine, Uwajima City Hospital
ABSTRACT
A 36-year-old man was diagnosed with G-CSF producing lung cancer (cStage IIB). The patient was scheduled for radical resection, but intraoperative findings revealed a nodule due to pleural seeding, and he was diagnosed with pStage IVA. Taking into consideration his persistent high fever due to G-CSF production from the tumor, decreased performance status, and resistance to chemotherapy, the patient underwent surgical resection to reduce the tumor volume and was administered carboplatin + paclitaxel + bevacizumab + atezolizumab for the remaining tumor. The tumor has remained recurrence-free to date after conversion to maintenance therapy with bevacizumab and atezolizu
KEYWORDS
Granulocyte colony-stimulating factor (G-CSF) producing lung cancer Multidisciplinary therapy Immune checkpoint inhibitor (ICI) Angiogenesis inhibitor
Received 25 Jan 2023 ／ Accepted 19 Jun 2023
AJRS, 12(5): 275-278, 2023
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