Annals of The Japanese Respiratory Society:A case of drug-induced lung injury suspected to be due to Euglena gracilis

Vol.12 No.5 Table of Contents

Abstract

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Article in Japanese

Case Report

A case of drug-induced lung injury suspected to be due to Euglena gracilis

Koki Fukushima^a Sumako Yoshioka^a Toyomitsu Sawai^a Nobuko Matsuo^a Junichi Kadota^a Hiroshi Mukae^b

^aDepartment of Respiratory Medicine, Nagasaki Harbor Medical Center
^bDepartment of Respiratory Medicine, Nagasaki University Hospital

ABSTRACT

This case concerns a 48-year-old, male non-smoker who presented to our department with a chief complaint of dyspnea on exertion. Fever and hypoxemia were observed, and computed tomography showed diffuse ground-glass appearance and consolidation in all lung fields. Bronchoalveolar lavage showed an increased number of eosinophil, and a drug-induced lymphocyte stimulation test (DLST) was positive for Euglena gracilis (supplement), leading to the diagnosis of drug-induced lung injury. Euglena gracilis was discontinued, and methylprednisolone (mPSL) 1,000 mg/day for 3 days was administered. The clinical symptoms and laboratory findings rapidly improved.

KEYWORDS

Euglena gracilis Drug-induced lymphocyte stimulation test (DLST) Drug-induced lung injury

Received 8 Jun 2023 ／ Accepted 14 Jul 2023

AJRS, 12(5): 251-255, 2023

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