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Abstract

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Article in Japanese

Case Report

A case of pleuroparenchymal fibroelastosis with Crohn's disease

Yuko Nitta  Yoshifumi Yamamoto  Takao Osa  Masahide Ohta  Shigeto Hontsu  Shigeo Muro 

Department of Respiratory Medicine, Nara Medical University

ABSTRACT

A 47-year-old man presented for evaluation of fever and cough. He reported a history of Crohn's disease and had been receiving mesalazine and infliximab therapy for 10 years. Chest computed tomography revealed decreased upper lobe volume, a right lobe apical cavity, and bilateral ground-glass opacification and consolidation. The patient was diagnosed with pleuroparenchymal fibroelastosis (PPFE) based on clinical and radiological findings. Aspergillus fumigatus was identified in bronchial lavage fluid culture, and a diagnosis of chronic pulmonary aspergillosis was made. Crohn's disease may be complicated by pulmonary manifestations including PPFE. In addition, it is necessary to consider infections and drug-induced lung injury in patients receiving immunosuppressive treatment for Crohn's disease.

KEYWORDS

Crohn's disease (CD)  Chronic pulmonary aspergillosis (CPA) 

Received 17 Nov 2022 / Accepted 18 Apr 2023

AJRS, 12(4): 196-200, 2023

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