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Article in Japanese
Abstract
Case Report
A case of suspected drug-induced pneumonia with concurrent methemoglobinemia
Tsukie Tsukuda Mayuka Yamane Junya Mizuta Yoshitaka Ogino Akihito Yokoyama
Department of Respiratory Medicine and Allergology, Kochi Medical School, Kochi University
ABSTRACT
An 86-year-old woman developed a fever of 38 °C and a dry cough two months after starting oral diaphenylsulfone for the treatment of psoriasis vulgaris. A chest computed tomography scan revealed ground-glass opacity and an elevated peripheral blood eosinophil count. We suspected drug-induced eosinophilic pneumonia; however, a marked decrease in SpO2 levels occurred during bronchoscopy. The bronchoscopy was discontinued, but arterial blood gas analysis revealed methemoglobinemia. We report herein a case where the assessment of pneumonia severity was affected by concurrent acquired methemoglobinemia and drug-induced pneumonia, both caused by diaphenylsulfone.
KEYWORDS
Methemoglobinemia Diaphenylsulfone (DDS) Drug-induced pneumonia
Received 20 Jan 2023 ／ Accepted 24 Feb 2023
AJRS, 12(3): 174-178, 2023
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