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Abstract
Original Article
Community-acquired primary viral pneumonia other than COVID-19 diagnosed via polymerase chain reaction results of bronchoalveolar lavage fluid
Kenji Takanoa Takashi Ishiguroa Yasuhito Kobayashib Riho Toribab Naomi Takatac Miyuki Uedac Yoshihiko Shimizub Noboru Takayanagia
aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Pathological Diagnosis, Saitama Cardiovascular and Respiratory Center
cDepartment of Radiology, Saitama Cardiovascular and Respiratory Center
ABSTRACT
We conducted a retrospective study of 67 patients with primary viral pneumonia (PVP) based on positive viral polymerase chain reaction (PCR) test results of bronchoalveolar lavage fluid.
Influenza virus was the most common (n=25), followed by common cold caused by coronavirus (n=23). The frequency of upper respiratory tract infection symptoms was found only in 25.4%. Some laboratory findings associated with COVID-19, such as lymphocytopenia and elevated D-dimer or ferritin levels, were also found, mainly in severe cases. Computed tomography showed bilateral consolidation (65.7%) and ground-glass opacities (89.6%). Patients received supportive care, antivirals, corticosteroids, or a combination thereof. In total, 13.4% of patients required mechanical ventilation, and the mortality rate for PVP was 6.0%. Prospective studies are needed to establish treatment strategies.
KEYWORDS
Primary viral pneumonia (PVP) Characteristic Influenza Antiviral Corticosteroid
Received 5 Sep 2022 ／ Accepted 19 Oct 2022
AJRS, 12(1): 2-10, 2023
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