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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of anti-ARS antibody-positive interstitial pneumonia managed with extracorporeal membrane oxygenation

Yuki Tsuneokaa,*  Hiromu Kawanoa  Sho Yamashitaa  Hisayuki Osoredaa  Shunsuke Kawaib  Tomonobu Kawaguchia 

aDepartment of Respirology, Japanese Red Cross Fukuoka Hospital
bDepartment of Cardiology, Japanese Red Cross Fukuoka Hospital
*Present address: Department of Respiratory Medicine, St. Mary's Hospital

ABSTRACT

A 49-year-old man was hospitalized with a diagnosis of pneumonia and treated with antibiotics. His respiratory condition worsened after admission and he was intubated and put on a ventilator. He was diagnosed with anti-ARS antibody-positive interstitial pneumonia so he received steroid pulse therapy and cyclophosphamide pulse therapy. The hypoxemia worsened; he was then placed on extracorporeal membrane oxygenation (ECMO). Eventually, the pneumonia symptoms improved and ECMO and ventilator were withdrawn. Later, serum creatine kinase levels increased and muscle symptoms appeared during immunosuppressant dose reduction. This case indicates that ECMO is an effective way to support patients diagnosed with polymyositis-related interstitial pneumonia with acute respiratory failure.

KEYWORDS

Anti aminoacyl-tRNA synthetase antibody (anti-ARS antibody)  Anti EJ antibody  Anti SS-A/Ro-52 antibody  Extracorporeal membrane oxygenation (ECMO) 

Received 14 Apr 2021 / Accepted 13 Dec 2021

AJRS, 11(2): 68-72, 2022

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