一般社団法人日本呼吸器学会 公式サイト
日本呼吸器学会英文誌 Respiratory Investigation
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集

Abstract

Full Text of PDF Full Text of PDF (667k)
Article in Japanese

Case Report

A case report of two rheumatoid arthritis patients with smoking-related interstitial pneumonia-like changes

Shiori Shonaia  Ryo Nagasawaa,*  Yu Haraa  Hisashi Hashimotoa  Koji Okuderab  Takeshi Kanekoa 

aDepartment of Pulmonology, Yokohama City University Graduate School of Medicine
bDepartment of Pathology, Yokohama City University Hospital
*Present address: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center

ABSTRACT

Smoking is important as a disease development and exacerbation factor in rheumatoid arthritis (RA) as well as in smoking-related interstitial pneumonia (SR-IP), including desquamative interstitial pneumonia (DIP), and respiratory bronchiolitis-associated with interstitial lung disease (RB-ILD). Case 1: A 64-year-old man who had stopped smoking 7 years previously. A medical check-up CT showed a right middle lobe nodular opacity and interstitial pneumonia. The right middle lobe resection specimen revealed respiratory bronchiolitis with lymphoid follicles and a DIP pattern. The patient developed RA 2 months after the operation. Case 2: A 68-year-old man had been diagnosed with RA 10 years earlier. IP developed 2 years later and he stopped smoking. The follow-up CT showed a nodule in the upper right lobe. The upper right lobe specimen revealed alveolitis with lymphoid follicles and an RB pattern. Cases with RA and SR-IP reactions are rare, and an RB pattern may have a more favorable prognosis than a DIP pattern.

KEYWORDS

Respiratory bronchiolitis-associated with interstitial lung disease (RB-ILD)  Rheumatoid arthritis (RA)  Desquamative interstitial pneumonia (DIP)  Connective tissue disease-associated interstitial lung disease  Smoking 

Received 24 Aug 2020 / Accepted 9 Sep 2021

AJRS, 10(6): 487-493, 2021

Google Scholar