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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

COVID-19-associated pulmonary aspergillosis: a case report

Yusuke Mori  Naoto Kubo  Yu Isoshima  Yasuhiko Nikaido  Teppei Hoshino 

Department of Respiratory Medicine, Kitakyushu City Yahata Hospital

ABSTRACT

A 76-year-old man was admitted to our hospital due to coronavirus disease 2019 (COVID-19). He eventually required intubation and mechanical ventilation due to progressive respiratory failure. A chest computed tomography (CT) scan, performed 14 days following the onset of symptoms, revealed a mass-like consolidation with surrounding ground-glass opacities in the lingular region of the left lung. He was diagnosed with COVID-19-associated pulmonary aspergillosis (CAPA) following a positive sputum culture and high serum antigen titer of Aspergillus fumigatus. Despite treatment with antifungal drugs, the patient died on day 43. Diagnosis and treatment of CAPA among intensive care unit patients is often challenging. Given the high mortality rate of CAPA, we should be aware of the possibility of this secondary infection in patients with severe COVID-19.

KEYWORDS

Coronavirus disease 2019 (COVID-19)  COVID-19-associated pulmonary aspergillosis (CAPA) Invasive pulmonary aspergillosis (IPA) 

Received 3 Jun 2021 / Accepted 21 Sep 2021

AJRS, 10(6): 472-476, 2021

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