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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of Sjögren's syndrome with left pleural effusion associated with suspected IgG4-related pleuritis

Takahiro Ando*  Kyoko Shimizu  Makiko Sugiura  Toshihide Fujie 

Department of Internal Medicine, Tokyo Metropolitan Ohtsuka Hospital
Present address: Department of Respiratory Medicine, Tokyo Medical and Dental University

ABSTRACT

A 76-year-old woman visited the hospital with left chest pain and malaise, and radiological findings showed left pleural effusion. Histological examination of the pleural biopsy showed fibrous thickening of the pleura and local IgG4-positive cells. On the other hand, she was diagnosed as having Sjögren's syndrome, based on xerostomia, xerophthalmia, and positive results for anti-Sjögren's syndrome (anti-SS-A/SS-B) antibodies. The left pleural effusion also showed an increase in anti-SS-A/SS-B antibodies. Soon after the initiation of corticosteroid administration, the left chest pain, malaise, and pleural effusion disappeared. We report a rare case of Sjögren's syndrome with left pleural effusion associated with suspected IgG4-related pleuritis.

KEYWORDS

IgG4-related disease  Sjögren's syndrome  Pleuritis 

Received 16 Feb 2021 / Accepted 12 Jul 2021

AJRS, 10(5): 421-426, 2021

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