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Abstract

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Article in Japanese

Case Report

A case of asthma and COPD overlap along with low eosinophil count after treatment for pulmonary aspergilloma with air-fluid levels in bullae

Satoru Teradaa  Hisako Matsumotoa  Akihiro Aoyamab  Kenta Nishia  Hiroshi Dateb  Toyohiro Hiraia 

aDepartment of Respiratory Medicine, Kyoto University Hospital
bDepartment of Thoracic Surgery, Kyoto University Hospital

ABSTRACT

A 68-year-old man had been treated for asthma and chronic obstructive pulmonary disease (COPD) overlap with inhaled corticosteroids and long-acting beta2-agonist. He presented with cough, wheezing, eosinophilia, and bullae with air-fluid levels in the upper right lobe of the lung. Since antimicrobial therapy failed to control the infected bullae, a thoracoscopic right upper lobectomy was performed. Eosinophilia improved after the procedure.
Filamentous fungi were present in the resected sample, which led to the diagnosis of pulmonary aspergillosis. Eosinophilia sometimes accompanies pulmonary aspergillosis but may improve with a reduction in the fungal load, as was observed in our case.

KEYWORDS

Asthma and COPD overlap  Pulmonary aspergilloma with air-fluid level in a bulla  Eosinophilia 

Received 19 Oct 2020 / Accepted 28 Jan 2021

AJRS, 10(3): 259-263, 2021

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