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日本呼吸器学会英文誌 Respiratory Investigation
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集

Abstract

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Article in Japanese

Case Report

A case of severe PVL-positive community-acquired MRSA pneumonia requiring multidisciplinary treatment with VV-ECMO

Tokuji Ikedaa,b  Shingo Ichibaa  Takahito Neic 

aDepartment of Surgical Intensive Care Medicine, Nippon Medical School Hospital
bEmergency and Critical Care Medical Center, Yamanashi Prefectural Central Hospital
cDepartment of Infection Control and Prevention, Nippon Medical School Hospital

ABSTRACT

We report a case of severe pneumonia secondary to methicillin-resistant Staphylococcus aureus (MRSA) in a 66-year-old healthy woman. She was unable to maintain adequate oxygenation even with mechanical ventilation owing to severe respiratory failure, necessitating veno-venous extracorporeal membrane oxygenation (VV-ECMO). We administered antibiotics, and the patient received appropriate systemic treatment; however, she died of necrotizing pneumonia that led to pulmonary suppuration. Genetic analysis confirmed that the isolated MRSA was community-acquired MRSA (CA-MRSA), and the Panton-Valentine leukocidin (PVL) gene was detected in this patient. Few CA-MRSA- and PVL-producing strains are observed in Japan; however, these strains may cause sporadic infections in future.

KEYWORDS

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) 

Received 26 Aug 2020 / Accepted 25 Nov 2020

AJRS, 10(2): 153-157, 2021

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