Full Text of PDF (512k)
Article in Japanese
Abstract
Case Report
Epstein-Barr virus-positive diffuse large B-cell lymphoma in an elderly patient that was difficult to diagnose using surgical lung biopsy: a case report
Mariko Hakamataa Masachika Hayashia Katsuaki Asakawaa Shin Watanabea Daisuke Ishikawab Toshiaki Kikuchia
aDepartment of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences
bDepartment of Respiratory Medicine, Niigata Prefectural Shibata Hospital
ABSTRACT
A 74-year-old man presented to his local physician with fever and cough. Chest radiography revealed bilateral lung shadows, and chest computed tomography revealed multiple nodular shadows and a ground-glass appearance in the bilateral lung fields. Transbronchial biopsy and surgical lung biopsy did not yield a definitive diagnosis. The ground-glass appearance and nodular shadows resolved after the patient received pulse steroid therapy; however, he died of progressive respiratory failure after corticosteroid treatment was tapered.
Autopsy evaluation revealed multiple lung tumors. Immunohistochemical examination revealed positive results for Epstein-Barr virus infection, and he was diagnosed with diffuse large B-cell lymphoma. Clinicians should consider this condition in patients who develop multiple tumor shadows in the lungs after steroid treatment.
KEYWORDS
Epstein-Barr virus-positive diffuse large B-cell lymphoma (EBV-positive DLBCL) Surgical lung biopsy (SLB) Multiple tumor shadows
Received 14 May 2020 ／ Accepted 17 Aug 2020
AJRS, 9(6): 458-462, 2020
Copyright © The Japanese Respiratory Society All Rights Reserved.