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Article in Japanese
Abstract
Original Article
Clinical analysis of 36 cases with malignant chest tumors in adolescent and young adult patients at our institution
Ai Shiwaku Jun Sakakibara Mamoru Kunisaki Megumi Furuta Yuta Takashima Hidenori Mizugaki Hajime Asahina Eiki Kikuchi Naofumi Shinagawa Satoshi Konno
Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
ABSTRACT
We conducted a retrospective analysis of 36 adolescent and young adult (AYA) patients with malignant chest tumors. Of those patients, 31 had lung cancer, 33 had performance status (PS) 0 or 1, and 35 had no comorbidities. Of 18 patients with lung adenocarcinoma, six had epidermal growth factor receptor (EGFR) mutations, and four had anaplastic lymphoma kinase (ALK) fusion genes. The median survival time of all patients and of the patients with lung cancer was 69.4 months and 32.8 months, respectively. AYA patient clinical characteristics, which are good PS, fewer comorbidities, and a prevalence of driver mutations, might contribute to a better prognosis for malignant chest tumors.
KEYWORDS
Adolescent and young adult generation Malignant chest tumor Patient clinical characteristic Prognosis
Received 25 Mar 2020 ／ Accepted 26 Jun 2020
AJRS, 9(5): 319-324, 2020
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