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Article in Japanese
Abstract
Case Report
A case of Good syndrome presenting with an axillary ulcer and complicated by multiple infectious diseases
Toru Kinouchia Takeshi Kawasakia Yasutaka Hirasawaa,b Shunichiro Iwasawaa Jiro Teradaa Koichiro Tatsumia
aDepartment of Respirology, Graduate School of Medicine, Chiba University
bDepartment of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University
ABSTRACT
A 58-year-old male presented to our emergency department because of an axillary ulcer on the right side, and he was hospitalized for the treatment of the skin and soft tissue infection. Additional workup identified a complicated anterior mediastinal tumor and oral candidiasis. The patient subsequently developed both Pneumocystis pneumonia and bacterial pneumonia. Biopsy of the mediastinal mass revealed type A thymoma, and blood testing showed hypogammaglobinemia, resulting in the diagnosis of Good syndrome. Treatment with trimethoprim-sulfamethoxazole, corticosteroids and immunoglobulin replacement therapy relieved the condition, leading to his discharge. Good syndrome is a cause of adult-onset immunodeficiency that should be considered for early intervention when an anterior mediastinal tumor is accompanied by multiple infection
KEYWORDS
Good syndrome Pneumocystis pneumonia (PCP) Thymoma Hypogammaglobulinemia Immunodeficiency
Received 25 Sep 2019 ／ Accepted 19 Dec 2019
AJRS, 9(2): 123-127, 2020
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