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Article in Japanese
Abstract
Case Report
A case of neuroblastoma in an adult
Takahito Suzukia,＊ Kazuhiro Asadaa Aya Muramatsub Makoto Suzukib Toshihiro Shiraia
aDepartment of Respiratory Medicine, Shizuoka General Hospital
bDepartment of Pathology, Shizuoka General Hospital
＊Present address: Division of Respiratory Medicine, Internal Medicine 2, Hamamatsu University Hospital
ABSTRACT
A 67-year-old man visited our hospital for the investigation of abnormal shadowing in the right inferior lobe and anterior mediastinum. He was diagnosed with neuroblastoma based on elevated levels of lactate dehydrogenase, neuron-specific enolase, and urinary vanillylmandelic acid, in addition to computed tomography-guided biopsy findings. First-line chemotherapy using ifosfamide (IFM), carboplatin (CBDCA), and etoposide (VP-16) resulted in a significant reduction in tumor volume. However, recurrence was detected 1 month after completion of six courses of chemotherapy. He died of the disease 10 months after presentation. Neuroblastoma in an adult is very rare; well-established treatments are therefore unavailable. Chemotherapy using IFM, CBDCA, and VP-16 is an option for effective treatment.
KEYWORDS
Neuroblastoma Adult onset Ifosfamide (IFM) Carboplatin (CBDCA) Etoposide (VP-16)
Received 31 Jul 2019 ／ Accepted 6 Nov 2019
AJRS, 9(2): 88-92, 2020
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