A 70-year-old man was referred to our hospital due to a mass lesion located in the right lower lung field on chest radiograph. Chest contrast-enhanced computed tomography (CT) revealed an extra-pulmonary lesion of 8cm in diameter attached to the right lower lobe of the lung. Because positron emission tomography (PET)/CT showed a localized uptake of ¹⁸F-fluorodeoxyglucose (FDG) on the pleural tumor, it was considered to be a solitary tumor. The patient underwent a tumor resection, including portions of the lower lobe of the right lung. The tumor cells were positive for calretinin, D2-40, and mesothelin, and negative for CEA and TTF-1, immunohistochemically. The tumor was histologically diagnosed as localized malignant pleural mesothelioma, epithelial type. After 4 months, recurrence of the tumor with pleural effusion was observed, and chemotherapies with cisplatin plus pemetrexed, pemetrexed only, and nivolumab were performed. The patient survived for five years after surgery. This is a rare case of localized malignant pleural mesothelioma with a long survival time.