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Abstract

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Article in Japanese

Case Report

A case of localized malignant pleural mesothelioma presenting as a giant solitary mass

Tomoko Yamadaa  Mitsuaki Sekiyaa,b  Satomi Shiotaa  Hitomi Joa  Yuki Tanabea  Kazuhisa Takahashia 

aDivision of Respiratory Medicine, Juntendo University, Faculty of Medicine and Graduate School of Medicine
bDepartment of Respiratory Medicine, Saiseikai Kawaguchi General Hospital

ABSTRACT

A 70-year-old man was referred to our hospital due to a mass lesion located in the right lower lung field on chest radiograph. Chest contrast-enhanced computed tomography (CT) revealed an extra-pulmonary lesion of 8cm in diameter attached to the right lower lobe of the lung. Because positron emission tomography (PET)/CT showed a localized uptake of 18F-fluorodeoxyglucose (FDG) on the pleural tumor, it was considered to be a solitary tumor. The patient underwent a tumor resection, including portions of the lower lobe of the right lung. The tumor cells were positive for calretinin, D2-40, and mesothelin, and negative for CEA and TTF-1, immunohistochemically. The tumor was histologically diagnosed as localized malignant pleural mesothelioma, epithelial type. After 4 months, recurrence of the tumor with pleural effusion was observed, and chemotherapies with cisplatin plus pemetrexed, pemetrexed only, and nivolumab were performed. The patient survived for five years after surgery. This is a rare case of localized malignant pleural mesothelioma with a long survival time.

KEYWORDS

Localized malignant pleural mesothelioma  Malignant pleural mesothelioma  Epithelial type 

Received 16 Apr 2019 / Accepted 28 May 2019

AJRS, 8(5): 317-321, 2019

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