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Abstract

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Article in Japanese

Case Report

Pulmonary mucosa-associated lymphoid tissue lymphoma post radiation therapy for breast cancer

Fumio Fujimori  Seitaro Abe  Takeshi Ota  Akira Youkou  Masato Makino  Yoshinari Tanabe 

Department of Respiratory Medicine, Niigata Prefectural Shibata Hospital

ABSTRACT

The patient was a 65-year-old woman who was diagnosed with right-sided breast cancer 8 years ago and was treated by mastectomy followed by chemotherapy and 50Gy of radiation therapy. Then 4 years later, her chest CT scan showed ground-glass opacification in contact with the irradiated area. Initially, the condition was thought to be radiation pneumonitis. However, gradually the mass became solid and extended in a belt-like manner. So, the patient was referred to our department and tissue biopsy was performed using endobronchial ultrasonography with a guide-sheath (EBUS-GS) and video-assisted thoracic surgery (VATS). The findings led to the final diagnosis of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma. Our search for references did not reveal any previous reports of pulmonary MALT lymphoma associated with radiation therapy, suggesting that it might be a rare condition. Our findings suggest that histological diagnosis is of critical importance in the clinical course of radiation pneumonitis, particularly in cases of exacerbation.

KEYWORDS

Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma  Breast cancer  Post radiation therapy  Endobronchial ultrasonography with a guide-sheath (EBUS-GS) 

Received 2 Apr 2019 / Accepted 15 May 2019

AJRS, 8(5): 312-316, 2019

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