A case of organizing pneumonia that required a differential diagnosis from lung cancer, with high 18F-fluorodeoxyglucose uptake in positron emission tomography
Shoko Isoyama Kosuke Hamai Hiroki Tanahashi Sayaka Ueno Takuya Tanimoto Nobuhisa Ishikawa
Department of Respiratory Medicine, Hiroshima Prefectural Hospital
A 50-year-old man was admitted to our hospital with chest pain. Chest unenhanced computed tomography (CT) revealed a mass in the left upper lobe of the lung and mediastinal poly-lymphadenopathy. Positron emission tomography images showed high uptake of 18F-fluorodeoxyglucose (FDG) in the lesions. Transbronchial lung biopsy and CT-guided biopsy specimens were taken from the area of the lung tumor with the highest FDG accumulation; a pathological diagnosis of organizing pneumonia was made. However, malignant lung disease was suspected because of elevated tumor marker levels and high uptake of FDG. Video-assisted thoracoscopic surgical biopsy of the mediastinal lymph nodes was performed, which revealed lung adenocarcinoma. This suggested that organizing pneumonia in the left upper lobe may be complicated by lung cancer.
Lung cancer Organizing pneumonia
Received 19 Oct 2018 / Accepted 6 Mar 2019
AJRS, 8(4): 298-301, 2019