Response to nivolumab in synchronous multiple primary cancers in the lungs and esophagus: a case report
Koji Kubotaa Keiko Mizunob Shunsuke Yasudaa Kousei Fukudaa Hiromasa Inoueb
aDepartment of Respiratory Medicine, Nanpuh Hospital
bDepartment of Pulmonary Medicine, Graduate School of Medical & Dental Sciences, Kagoshima University
A 69-year-old man who was diagnosed with stage IIIB synchronous primary lung squamous cell carcinoma and esophageal squamous cell carcinoma was administered as continuous chemotherapy. His performance status was good, so we initiated nivolumab as sixth-line chemotherapy. The tumor sizes in both the lungs and esophagus then significantly reduced after initial pseudoprogression. We report here a rare case of synchronous multiple primary cancers effectively treated with immune checkpoint inhibitors.
Nivolumab Multiple primary cancers Lung cancer Immune checkpoint inhibitor
Received 13 Mar 2019 / Accepted 7 May 2019
AJRS, 8(4): 273-277, 2019