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Abstract

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Article in Japanese

Case Report

Response to nivolumab in synchronous multiple primary cancers in the lungs and esophagus: a case report

Koji Kubotaa  Keiko Mizunob  Shunsuke Yasudaa  Kousei Fukudaa  Hiromasa Inoueb 

aDepartment of Respiratory Medicine, Nanpuh Hospital
bDepartment of Pulmonary Medicine, Graduate School of Medical & Dental Sciences, Kagoshima University

ABSTRACT

A 69-year-old man who was diagnosed with stage IIIB synchronous primary lung squamous cell carcinoma and esophageal squamous cell carcinoma was administered as continuous chemotherapy. His performance status was good, so we initiated nivolumab as sixth-line chemotherapy. The tumor sizes in both the lungs and esophagus then significantly reduced after initial pseudoprogression. We report here a rare case of synchronous multiple primary cancers effectively treated with immune checkpoint inhibitors.

KEYWORDS

Nivolumab  Multiple primary cancers  Lung cancer  Immune checkpoint inhibitor 

Received 13 Mar 2019 / Accepted 7 May 2019

AJRS, 8(4): 273-277, 2019

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