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Abstract
Case Report
Spontaneous improvement of anti-EJ antibody-positive interstitial pneumonia
Yuji Inagakia Chikatoshi Sugimotoa,b Toru Araia,b Takahiko Kasaib,c Yuko Abea Yoshikazu Inouea,b
aDepartment of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center
bClinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center
cDepartment of Pathology, National Hospital Organization Kinki-Chuo Chest Medical Center
ABSTRACT
A 62-year-old woman presented at our hospital complaining of dyspnea on exertion, dry cough, and dry eye. On physical examination, she had no muscle weakness or skin symptoms. Chest high-resolution computed tomography (HRCT) showed consolidation and ground-glass opacities, predominantly in the lower lung zones. Serological examination revealed the presence of anti-EJ antibody. We performed a video-assisted thoracic surgical lung biopsy and the pathological diagnosis was fibrotic nonspecific interstitial pneumonia with organizing pneumonia. Her symptoms, laboratory findings, pulmonary function tests, and lung lesions improved spontaneously. Careful observation without immunosuppressive therapy could be an option for the management of patients with interstitial pneumonia with positive anti-EJ antibody.
KEYWORDS
Anti-aminoacyl tRNA synthetase antibody syndrome Anti-EJ antibody
Received 8 Dec 2018 ／ Accepted 11 Mar 2019
AJRS, 8(4): 255-258, 2019
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