Coral broncholith associated with granulomatosis with polyangiitis and tracheobronchomalacia
Mitsuru Imamura* Toshiaki Shimizu Oh Sasaki Hiroaki Harada Makoto Dohi Kazuhiko Yamamoto
Department of Allergy and Rheumatology, the University of Tokyo Hospital
*Present address: Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine
A 75-year-old woman suffering from granulomatosis with polyangiitis (GPA), under treatment with corticosteroids, was followed up in our hospital. She had a chronic bronchial infection and tracheobronchomalacia. Chest unenhanced computed tomography showed a calcified lesion in the left bronchus and peripheral atelectasis of the left upper lobe. Repeat bronchoscopies over 3 years had shown a “coral” lesion arising from the left second carina, which progressively increased in size. The lesion was finally removed under bronchoscopy. Histology showed nodular hyaline cartilage with peripheral calcification. The diagnosis of a coral broncholith was made. This is the first report of a patient in whom the following coexisted: a broncholith with GPA, a broncholith with tracheobronchomalacia, or GPA with tracheobronchomalacia, respectively.
Coral broncholith Granulomatosis with polyangiitis (GPA) Tracheobronchomalacia (TBM)
Received 27 Nov 2017 / Accepted 22 May 2018
AJRS, 7(5): 332-337, 2018