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Article in Japanese
Abstract
Case Report
A case of lung adenocarcinoma associated with Trousseau syndrome successfully treated with nivolumab therapy
Kohei Fujita Makoto Nakao Sosuke Arakawa Yusuke Sakai Yuto Suzuki Hideki Muramatsu
Department of Respiratory Medicine, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives
ABSTRACT
A 59-year-old man was referred to our hospital because of cervical lymphadenopathy. Chest-computed tomography showed a nodular shadow on the left upper lobe of the lung, and cervical and mediastinal lymphadenopathy. Biopsy specimens from the left posterior cervical lymph node revealed adenocarcinoma of the lung. He was treated with carboplatin with pemetrexed followed by pemextred alone for six months. However, cerebral infarction occurred, and he was diagnosed with Trousseau syndrome associated with lung adenocarcinoma. He received anticoagulation with heparin by subcutaneous injection and nivolumab monotherapy for 11 months. Although Trousseau syndrome is associated with a poor prognosis, the administration of heparin and nivolumab was successful in controlling the condition in this particular case.
KEYWORDS
Trousseau syndrome Nivolumab Lung adenocarcinoma
Received 31 Mar 2018 ／ Accepted 6 Jul 2018
AJRS, 7(5): 316-320, 2018
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