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Abstract

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Article in Japanese

Case Report

Two cases of advanced non-small cell lung cancer on hemodialysis treated with pembrolizumab

Katsuaki Yazawaa  Masahumi Doib  Hiroki Ikurab  Mayumi Fujiib  Yoshikazu Tsukadab 

aDepartment of Pulmonary Medicine, Ome Municipal General Hospital
bDepartment of Pulmonary Medicine, Soka Municipal Hospital

ABSTRACT

Case 1: A 70-year-old male with end-stage renal disease (ESRD) on hemodialysis was referred to our hospital with abnormal right upper lobe shadowing on chest X-ray. He was diagnosed with stage IIIB squamous cell carcinoma (tumor proportion score: 50%‒60%). Pembrolizumab was administered ten times and tolerated. Case 2: A 79-year-old male with ESRD on hemodialysis was referred to our hospital with abnormal right middle lobe shadowing on chest X-ray. He was diagnosed with stage IIIA adenocarcinoma (tumor proportion score: 50%‒74%). Pembrolizumab was administered. A cerebral infarction occurred after a few days and pembrolizumab was withdrawn. Pembrolizumab can be considered as a treatment option in non-small cell lung cancer patients with ESRD on hemodialysis.

KEYWORDS

Chronic kidney disease  Hemodialysis  Non-small cell lung cancer  Anti PD-1 antibody  Pembrolizumab 

Received 22 Feb 2018 / Accepted 12 Jun 2018

AJRS, 7(5): 306-310, 2018

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