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Abstract

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Article in Japanese

Case Report

A case of lung metastases of angiosarcoma with diffuse alveolar hemorrhage

Hideto Oshita  Shoko Isoyama  Ayaka Yoshida  Keiko Osaki  Kohei Kawasaki  Ken Okusaki 

Department of Internal Medicine, Mihara Medical Association Hospital

ABSTRACT

An 85-year-old man presented to our hospital with hemoptysis and subcutaneous masses. Unenhanced computed tomography (CT) scan revealed multiple tumors of the chest wall, vertebrae, and ilium. We performed a needle biopsy of a subcutaneous tumor on the left lower back, and a diagnosis of angiosarcoma was made. CT scan also revealed multiple small nodules together with ground-glass opacities bilaterally in the peripheral lung fields. Bronchoscopy with bronchoalveolar lavage (BAL) was performed with progressively bloody BAL returns. Bronchial brush cytology showed hemosiderin-laden macrophages and atypical spindle-shaped cells, corresponding to metastatic angiosarcoma. We concluded that metastatic lung angiosarcoma was the cause of the diffuse alveolar hemorrhage (DAH). Although angiosarcoma is an extremely rare malignant neoplasm, it frequently leads to DAH originating from pulmonary lesions and should be included in a differential diagnosis of DAH.

KEYWORDS

Angiosarcoma  Metastatic lung tumor  Diffuse alveolar hemorrhage (DAH) 

Received 30 Mar 2018 / Accepted 31 May 2018

AJRS, 7(5): 301-305, 2018

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