一般社団法人日本呼吸器学会 公式サイト
日本呼吸器学会英文誌 Respiratory Investigation
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 検索用
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 全文PDF

Abstract

Full Text of PDF Full Text of PDF (865k)
Article in Japanese

Case Report

A case of acute fibrinous and organizing pneumonia with recurrent exacerbations

Norihiko Nakanishia  Yuji Ohtsukib  Kazuhiko Saekia  Junya Nakamuraa  Masaaki Shiojiria  Haruka Kondoha 

aDepartment of Respirology, Ehime Prefectural Central Hospital
bDepartment of Diagnostic Pathology, Matsuyama Shimin Hospital

ABSTRACT

Organizing pneumonia (OP) is recognized as a disease entity with a good prognosis. Recently, a new disease entity — acute fibrinous and organizing pneumonia (AFOP) — has been identified which has a poor prognosis.
We report a case of AFOP with recurrent exacerbations after steroid tapering. A 43-year-old man developed cough, fever, and exertional dyspnea. Chest X-ray and high-resolution computed tomography showed patchy, bilateral infiltrative shadows on the lung fields. Transbronchial lung biopsy specimens revealed OP with intraluminal organization and fibrin deposits. We considered that the patient had AFOP, and steroid therapy was started. Abnormal chest shadows disappeared; however, new infiltrates appeared after steroid tapering. Additional cyclosporine A was effective. AFOP should be recognized as an OP in which long-term therapy is effective.

KEYWORDS

Organizing pneumonia (OP)  Acute fibrinous and organizing pneumonia (AFOP)  Recurrent exacerbations  Steroid therapy 

Received 25 Aug 2017 / Accepted 7 May 2018

AJRS, 7(4): 245-249, 2018

Google Scholar