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Abstract

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Article in Japanese

Case Report

Three cases of interstitial pneumonia with anti-aminoacyl tRNA synthetase antibodies complicated by gynecological cancer

Eito Yokoia  Yuki Harutab  Yukiko Wadab  Hiroshi Itob  Kazuhiko Machidab  Masaki Matsuob 

aDepartment of Respiratory Medicine, Nagoya University Hospital
bDepartment of Respiratory Medicine, Chubu Rosai Hospital

ABSTRACT

We report three cases of patients with interstitial pneumonia who were positive for anti-aminoacyl tRNA synthetase (ARS) antibodies. Screening for cancer revealed cervical cancer in two cases and endometrial cancer in the third case. In all the cases, interstitial pneumonia responded well to treatment; however, one patient died due to progression of the cancer. Until now, an association between anti-ARS antibodies and cancer has not been reported; however, there is no clear opinion on such an association. Here we report three cases of interstitial pneumonia carrying anti-ARS antibodies complicated by the presence of gynecological cancer in a single establishment and over a short period of time.

KEYWORDS

Anti-aminoacyl tRNA synthetase (ARS) antibody  Interstitial pneumonia  Malignancy  Gynecological tumor 

Received 6 Nov 2017 / Accepted 28 Mar 2018

AJRS, 7(4): 229-233, 2018

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