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Article in Japanese
Abstract
Case Report
A case of carboplatin-induced colitis resembling ulcerative colitis
Akihiro Yoshimura Shinsuke Shiotsu Sayaka Uda Naoko Kurisu Tomoya Sagawa Noriya Hiraoka
Department of Respiratory Medicine, Japanese Red Cross Kyoto Daiichi Hospital
ABSTRACT
A 47-year-old man was diagnosed with locally advanced non-small cell carcinoma and received chemoradiation therapy with carboplatin/paclitaxel. During therapy he suddenly noticed blood in his stools, and colonoscopy revealed what was suspected to be ulcerative colitis. However, we considered the colitis to be drug-induced from carboplatin, because the bloody stool resolved without treatment. Our search of the literature revealed no reports of carboplatin causing colitis that on endoscopy resembles ulcerative colitis. It should therefore be noted that colitis is one of the hypersensitivity reactions that can be caused by carboplatin.
KEYWORDS
Drug-induced colitis Ulcerative colitis Non-small cell lung cancer Carboplatin Type Ⅳ allergy
Received 20 Feb 2017 ／ Accepted 7 Aug 2017
AJRS, 6(6): 441-444, 2017
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