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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of lung nodule caused by Schizophyllum commune that was diminished by liposomal amphotericin B

Shoko Kawaia,b  Miake Yamamotoa  Miyako Kitazonoa  Kengo Murataa  Akihiko Wadaa  Mikio Takamoria 

aDepartment of Respiratory Medicine, Tokyo Metropolitan Tama Medical Center
bDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center

ABSTRACT

A 59-year-old woman with myelodysplastic syndromes was admitted to the Tokyo Metropolitan Tama Medical Center to undergo an umbilical cord blood transplant. A lung nodule was found by computed tomography 2 months after administration, and Schizophyllum commune was cultured from her sputum. Serum immunoglobulin G against S. commune was positive, and she was diagnosed as having lung nodule caused by S. commune. She was treated with liposomal amphotericin B, and the nodule diminished. Including our case, 6 cases of lung infection resulting from S. commune have been reported. Infection by S. commune should be included in the differential diagnosis of a lung nodule in immunocompromised patients. Further collection of such cases is required.

KEYWORDS

Schizophyllum commune  Liposomal amphotericin B  Myelodysplastic syndromes  Umbilical cord blood transplant 

Received 18 Aug 2016 / Accepted 20 Jan 2017

AJRS, 6(3): 165-169, 2017

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