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Abstract
Case Report
A case of primary effusion lymphoma-like lymphoma with asbestos exposure
Rie Anazawaa,b Masakazu Konob Toshihiko Sakaib Saori Shionoc Hirokazu Tojimab
aDepartment of Respiratory Medicine, Chiba University Hospital
bDepartment of Respiratory Medicine, Tokyo Rosai Hospital
cDepartment of Pathology, Tokyo Rosai Hospital
ABSTRACT
This case involves a 76-year-old male patient with a history of asbestos exposure at construction sites. During follow-up for pleural plaques and pleural effusion, the pleural effusion and a thoracoscopic examination resulted in a diagnosis of malignant lymphoma (ML) confined to the pleural effusion/pleura and without mass formation. Of the malignant lymphomas, primary effusion lymphoma (PEL) is a disease that proliferates only in fluid-filled body cavities; however, cases that resemble PEL with no immunodeficiency and that test negative for human herpes virus 8 (HHV-8) have come to be interpreted as PEL-like lymphoma (PEL-LL). The patient in this case had diffuse large B-cell malignant lymphoma confined to the pleural effusion/pleura and was negative for HHV-8; he was therefore diagnosed with PEL-LL. Chronic pleuritis resulting from asbestos may have influenced an onset of ML in this case.
KEYWORDS
Asbestos Pleural effusion Primary effusion lymphoma-like lymphoma
Received 31 Jan 2016 ／ Accepted 12 May 2016
AJRS, 5(5): 269-273, 2016
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