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Abstract

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Article in Japanese

Case Report

A case of Trousseau syndrome associated with squamous cell lung cancer

Ryota Aoki  Kosuke Kashiwabara  Shinji Fujii  Shinsuke Tsumura  Hiroshi Semba 

Department of Respiratory Medicine, Kumamoto Regional Medical Center

ABSTRACT

An 84-year-old man with pulmonary squamous cell carcinoma (cT1bN3M1a; stage IV) in the left upper lobe, and the carcinomatous pleurisy received talc pleurodesis. He had a sudden onset of hemiplegia before the initiation of anticancer chemotherapy. A brain MRI test showed multiple high-intensity signals in the right cerebellar hemisphere and both sides of cerebral cortex. Although there were no other risk factors for hypercoagulation, brain infarctions continued to deteriorate under anticoagulant therapy. He was diagnosed as having Trousseau syndrome associated with primary lung cancer. An additional anticancer therapy (tegafur-gimeracil-oteracil potassium 80 mg/body) did not improve his condition, and he died of aspiration pneumonia on hospital day 20. We report a rare case of Trousseau syndrome occurring in patients with pulmonary squamous cell carcinoma.

KEYWORDS

Trousseau syndrome  Cerebral thrombosis  Squamous cell lung cancer 

Received 6 Jun 2015 / Accepted 24 Sep 2015

AJRS, 5(1): 3-7, 2016

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