
Article in Japanese
A case of autoimmune pulmonary alveolar proteinosis with non-tuberculous mycobacteriosis improved by antibiotics chemotherapy
Sayaka Tachibana Kouji Inoue Kazuhiko Saeki Masaaki Shiojiri Norihiko Nakanishi Tomonori Moritaka
Department of Respiratory Medicine, Ehime Prefectural Central Hospital
A 51-year-old man was admitted because of dyspnea on effort, and his chest image showed bilateral diffuse ground-glass opacity and cavitary infiltration in the left upper lobe. We made a diagnosis of pulmonary alveolar proteinosis (PAP) for a milky bronchoalveolar lavage fluid, and complication of Mycobacterium avium complex (MAC) infection was confirmed by smear, culture, and polymerase chain reaction in a sample of the cavity lesion. Whole-lung lavage was necessary in both lungs for the treatment of his respiratory failure, but because it had a risk of dissemination of MAC, we carried out whole-lung lavage only in the right lung. After that, we continued the antibiotics use for MAC, and his chest image improved, not only the infectious lesion, but also PAP in the left lung.
Pulmonary alveolar proteinosis Non-tuberculous mycobacteriosis Mycobacterium avium complex
Received 3 Feb 2015 / Accepted 17 Jun 2015
AJRS, 4(6): 478-482, 2015