A case of angioimmunoblastic T-cell lymphoma with multiple pulmonary nodules and interstitial shadow that were resolved in two months
Yuka Mishimaa Reina Imasea Tamon Yagia Tomoyuki Ogataa Kimitake Tsuchiyab Naohiko Inaseb
aDepartment of Respiratory Medicine, JA Toride Medical Center
bDepartment of Respiratory Medicine, Tokyo Medical and Dental University
The patient was a 71-year-old woman who had experienced a skin biopsy for generalized eruption three months earlier. She had been diagnosed with angioimmunoblastic T-cell lymphoma (AITL), since the pathological findings showed CD3+/CD10+ lymphocytes infiltration with dysplasia. She was referred to our department for her chronic cough, and chest computed tomography showed multiple pulmonary nodules and a diffuse interstitial shadow mainly in the bilateral lower lobes. Aggregation of CD3+ lymphocytes with mild atypia and scattered microgranulomas were detected in the lung tissue obtained by thoracoscopic lung biopsy. These findings were considered as reactive lymphocyte accumulation and sarcoid reaction associated with AITL. Spontaneous remission of the shadows was achieved with no treatment in two months.
Angioimmunoblastic T-cell lymphoma (AITL) Pulmonary nodule Interstitial shadow Sarcoid reaction
Received 11 Oct 2014 / Accepted 16 Feb 2015
AJRS, 4(3): 240-243, 2015