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Article in Japanese
Abstract
Case Report
A case report of adenocarcinoma of the lung with miliary brain metastases that began to show calcification during treatment
Yoshie Moritaa Taro Okumurab Takuto Sakashitab Michio Shigematsub
aDivision of Pulmonary Medicine, Kyoto Prefectural University of Medicine
bDepartment of Respiratory Medicine, Sumitomo Hospital
ABSTRACT
A 63-year-old woman was referred to our hospital because of body weight loss, cognition impairment, and peripheral circulatory failure. She was diagnosed as having adenocarcinoma of the lung with EGFR mutation (exon 21, L858R), miliary brain metastases, carcinomatous meningitis, and disseminated intravascular coagulation (DIC). Gefitinib was started, and after 3 or 4 weeks, cognition impairment and DIC improved temporarily. Subsequently she took whole brain irradiation, received home care for 3 months with gefitinib, and died 6.5 months after diagnosis. A brain CT scan taken 6 weeks before death showed numerous miliary calcifications in metastatic sites, which were not found 2 months before. We report a case of adenocarcinoma of the lung with miliary brain metastases that eventually showed calcification during a short period.
KEYWORDS
Miliary brain metastases Calcification Adenocarcinoma of the lung Carcinomatous meningitis
Received 5 Jun 2014 ／ Accepted 30 Dec 2014
AJRS, 4(3): 227-230, 2015
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