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Abstract

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Article in Japanese

Case Report

A case of microscopic polyangiitis developed while observation of suspicious chronic hypersensitivity pneumonitis

Koichiro Takahashi  Hiroki Tashiro  Go Kato  Naoko Arakane  Shinichiro Hayashi 

Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University

ABSTRACT

A 63-year-old man was admitted for evaluation of shortness of breath that had appeared in March 2010. A ground-glass opacity and a reticular shadow were shown on chest CT. He has engaged in making buns in a bakery, which is associated with exposure to flour dust. He was diagnosed as chronic hypersensitivity pneumonia caused by flour dust inhalation because ground-glass opacity on CT was improved after isolation from the flour dust. On March 2011, fever, arthralgia, and skin rash appeared. He was diagnosed as microscopic polyangiitis (MPA) from a skin biopsy and a positive MPO-ANCA test. However, the interstitial shadows on CT did not change at this point. MPA symptoms were improved in the treatment of glucocorticoid therapy. Here we report that a case of chronic hypersensitivity pneumonia as chronic inflammation may cause secondary vasculitis.

KEYWORDS

Chronic hypersensitivity pneumonitis  Microscopic polyangiitis  Interstitial pneumonia 

Received 17 Sep 2014 / Accepted 18 Nov 2014

AJRS, 4(2): 189-193, 2015

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