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Abstract

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Article in Japanese

Case Report

A case of hypereosinophilic syndrome with eosinophilic infiltration, pulmonary thromboembolism, and deep venous thrombosis

Seishi Higashia,b  Youko Suzukib  Naoki Nishiyamab,c  Wataru Ejimab  Rinako Yamashitab  Reiko Takib 

aDivision of Respiratory Medicine, Tokyo Medical and Dental University
bDivision of Respiratory Medicine, Musashino Red Cross Hospital
cDivision of Respiratory Medicine, Tsuchiura Kyodo General Hospital

ABSTRACT

A 55-year-old man presented with high fever and dyspnea. A chest X-ray and a chest CT scan showed diffuse infiltration in both lungs, and laboratory findings revealed severe eosinophilia in both peripheral blood and bronchoalveolar lavage fluid (BALF). Further examinations led to a diagnosis of hypereosinophilic syndrome (HES) with disseminated intravascular coagulation (DIC). Corticosteroid therapy rapidly reduced eosinophilia and pulmonary infiltration, but the DIC stage remained, suggesting that thromboembolism was complicated. The postcontrast CT scan showed pulmonary thromboembolism and deep venous thrombosis, which were successfully treated with warfarin. Interestingly, on CT scans we could distinguish consolidations of pulmonary infarction from diffuse eosinophilic infiltration.

KEYWORDS

Hypereosinophilic syndrome  Pulmonary thromboembolism  DIC 

Received 14 Jun 2014 / Accepted 20 Oct 2014

AJRS, 4(1): 86-90, 2015

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