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Article in Japanese
Abstract
Case Report
A case of lung cancer complicating pneumatosis intestinalis during beyond progressive disease therapy
Ai Yamamotoa Naoshi Kikuchia Kazutoshi Isobea Tomohiro Wadaa Kazutoshi Shibuyab Sakae Hommaa
aDepartment of Respiratory Medicine, Toho University Omori Medical Center
bSurgical Pathology, Toho University Omori Medical Center
ABSTRACT
A 70-year-old female was diagnosed as adenocarcinoma of the lung with epidermal growth factor receptor mutation (cT4N1M1b stage IV). She was treated with erlotinib (150 mg daily) for 8 months, but the primary site showed progressive disease (PD). She received beyond PD therapy with continuous erlotinib added on pemetrexed (500 mg/body, by 3 weeks). Nine days after the third course started, she developed nausea, vomiting, diarrhea, and stomachache. The abdominal computed tomography (CT) showed gas in the ascending and transverse colon walls. Therefore she was diagnosed as pneumatosis intestinalis (PI). This is the first reported case of lung cancer complicating with PI during beyond PD therapy with pemetrexed and erlotinib.
KEYWORDS
Pneumatosis intestinalis Primary lung cancer Beyond PD Pemetrexed Erlotinib
Received 20 Sep 2013 ／ Accepted 13 Feb 2014
AJRS, 3(4): 548-552, 2014
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