Clinical phenotypes of chronic obstructive pulmonary disease and potentialities of order-made medical managements
Tomotaka Kawayama Takashi Kinoshita Kazuko Matsunaga Akira Sakamoto Tomoaki Hoshino
Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine
The term phenotypes in chronic obstructive pulmonary diseases (COPD) is defined as “the groups with several obviously different clinical conditions and prognoses between individuals with COPD despite a definitive diagnosis of COPD in accordance with the same criteria.” COPD is recognized not only as a respiratory disease, but also as a syndrome with systemic and heterogeneous diseases. We have recently begun to recognize that numerous respiratory medicines, such as long-acting bronchodilator and anti-inflammatory drugs, are contributing to the prevention and cure of COPD. Nevertheless, COPD is still an incompletely curative disease. The classifications of phenotypes will be necessary to choose the best combinations of managements in COPD.
Chronic obstructive pulmonary disease (COPD) Emphysema Chronic bronchitis Phenotype
AJRS, 3(3): 329-336, 2014