一般社団法人日本呼吸器学会 公式サイト
日本呼吸器学会英文誌 Respiratory Investigation
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 検索用
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 全文PDF

Abstract

Full Text of PDF Full Text of PDF (1317k)
Article in Japanese

Topics Series Advances in lung cancer therapy

Update on pathological diagnosis: The new adenocarcinoma classification and morphological characteristics of adenocarcinomas with recently identified gene alterations

Yasushi Yatabe 

Department of Pathology and Molecular Diagnostics, Aichi Cancer Center

ABSTRACT

In addition to classical histological diagnosis, patient selection for personalized medicine is appended to a current role of pathological diagnosis. In 2001, a new adenocarcinoma classification was proposed, presenting new concepts of lung cancers. Since then, the new classification has been applied in clinical practice, and the results have been reported. In this article, we briefly review this classification and discuss the practical problem in applying it to clinical practice. Moreover, we review the pathological-molecular correlation of the novel gene alterations that were identified after publication of the new classification.

KEYWORDS

Lung adenocarcinoma  IASLC/ATS/ERS adenocarcinoma classification  ROS1  RET  NRG1 

AJRS, 3(1): 16-22, 2014

Google Scholar