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Article in Japanese
Abstract
Case Report
A case of pulmonary adenocarcinoma accompanied by antiphospholipid syndrome
Hiroki Otaa Kazutoshi Isobea Keishi Suginoa Atsuo Ichikawaa Megumi Wakayamab Sakae Hommaa
aDepartment of Respiratory Medicine, Toho University Omori Medical Center
bDepartment of Surgical Pathology, Toho University School of Medicine
ABSTRACT
A 59-year-old man was admitted to our hospital complaining of dyspnea on exertion. Chest contrast-enhanced computed tomography revealed swelling of the right hilar and mediastinal lymph nodes with thrombosis in the pulmonary arteries. After insertion of an umbrella in the inferior vena cava, the patient underwent endobronchial ultrasonography (EBUS). He was diagnosed as having cTxN3M0 stage IIIB pulmonary adenocarcinoma associated with antiphospholipid syndrome resulting from a high level of anticardiolipin antibody. Four courses of chemotherapy (carboplatin/paclitaxel) with radiation 50 Gy resulted in decreases in lymph node swelling and anticardiolipin antibody level. Antiphospholipid syndrome in this case was considered to be a paraneoplastic syndrome caused by pulmonary adenocarcinoma.
KEYWORDS
Lung cancer Antiphospholipid syndrome Paraneoplastic syndrome
Received 14 Feb 2013 ／ Accepted 3 Jun 2013
AJRS, 2(5): 612-616, 2013
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