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Abstract

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Article in Japanese

Case Report

A case of disseminated Mycobacterium avium infection in a non-AIDS patient

Towa Uzua  Hirofumi Matsuokaa  Midori Koyamaa  Yasuko Komaa  Kensuke Fukumitsua  Yoshitaka Kasaia  Daiki Masuyaa  Harukazu Yoshimatsua  Akira Hebisawab  Yujiro Suzukia 

aDepartment of Respiratory Medicine, Shinko Hospital
bDepartment of Pathology and Clinical Laboratories, National Hospital Organization Tokyo National Hospital

ABSTRACT

An 81-year-old woman was admitted to our hospital because of low-grade fever for 2 months. Chest computed tomography (CT) showed diffuse small nodular shadows in both lung fields. Bronchofiberscopy was performed, and Mycobacterium avium was cultured from a specimen. The patient underwent video-assisted thoracoscopic lung biopsy. Histological findings showed subpleural and perivascular granulomas, which indicated hematogenous dissemination of mycobacteria. M. avium was cultured from biopsy specimens, and the patient was diagnosed with disseminated nontuberculous mycobacteriosis. She was treated with clarithromycin, rifampicin, ethambutol, and amikacin, and the small nodular shadows on chest CT subsequently dissolved. The patient was human immunodeficiency virus (HIV)-antibody negative, and we could not identify any other immunodeficiency diseases.

KEYWORDS

Disseminated nontuberculous mycobacteriosis  Mycobacterium avium 

Received 9 Jul 2012 / Accepted 29 Aug 2012

AJRS, 2(2): 153-156, 2013

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