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Article in Japanese
Abstract
Case Report
A case of pulmonary malignant lymphoma demonstrating spontaneous regression after discontinuation of methotrexate therapy for rheumatoid arthritis
Hanako Koguchia Yutaka Takeuchia Eiki Kikuchia Satoshi Oizumia Yoshihiro Matsunob Masaharu Nishimuraa
aFirst Department of Medicine, Hokkaido University School of Medicine
bDepartment of Pathology, Hokkaido University Hospital
ABSTRACT
Primary pulmonary lymphoma (PPL) is a relatively rare disease. It represents only 0.3% of non-Hodgkin's lymphoma and only 0.5–1% of primary pulmonary malignancies. Lymphoproliferative disorders (LPD), which occur in patients taking immunosuppressive drugs, are known as immunodeficiency-related LPD. Among them, methotrexate (MTX)-related LPD, which occurs in patients with rheumatoid arthritis (RA), is the most representative. Herein we describe a case of PPL, which demonstrated spontaneous regression after discontinuation of the MTX therapy for RA.
KEYWORDS
Pulmonary malignancy Immunodeficiency-related lymphoproliferative disorders Rheumatoid arthritis Spontaneous regression
Received 20 Sep 2011 ／ Accepted 16 Dec 2011
AJRS, 1(3): 256-260, 2012
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