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Abstract

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Article in Japanese

Case Report

A case of secondary pulmonary alveolar proteinosis during glucocorticoid therapy for interstitial pneumonia complicated by HTLV-1 carrier

Tetsuo Fujitaa,b  Yasushi Tanimotoc  Akihiko Taniguchic  Daisuke Nojimac  Yoshihiro Mikib  Kazuhiro Tomitab  Hidenori Nakamurab 

a Department of Respiratory Medicine, Chiba University School of Medicine
b Department of Respiratory Medicine, Seirei Hamamatsu General Hospital
c Department of Respiratory Medicine, Okayama University School of Medicine

ABSTRACT

A 44-year-old man with HTLV-1 carrier was admitted to our hospital because of persistent cough and presence of ground-glass opacities in the lower fields of both lungs. We had diagnosed him with interstitial lung disease because of the findings of a chest CT scan and a bronchoalveolar lavage fluid analysis. Although glucocorticoid therapy was started, pulmonary aspergillosis was complicated, and his respiratory failure has deteriorated in parallel with the worsening in lung opacity. After reevaluating his clinical course, chest CT scan findings, and a PAS-stained specimen obtained by transbronchial lung biopsy, we have diagnosed his disease as pulmonary alveolar proteinosis. We have treated him with whole-lung lavage under general anesthesia. These treatments were effective for his respiratory failure and radiographic findings.

KEYWORDS

Pulmonary alveolar proteinosis  HTLV-1 associated bronchiolo-alveolar disorder  Whole lung lavage  Pulmonary aspergillosis 

Received 1 Jun 2011 / Accepted 26 Oct 2011

AJRS, 1(2): 129-134, 2012

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