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Abstract

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Article in Japanese

Case Report

Intravascular large B-cell lymphoma in which pulmonary artery wedge aspiration cytology was useful for differential diagnosis

Takashi Ishiguroa  Akira Nonoueb  Masahisa Kudoc  Yu Nishimurad  Yoshihiko Shimizue 

aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Cardiology, Saitama Cardiovascular and Respiratory Center
cDepartment of Hematology, Saitama Cancer Center
dDepartment of Pathology, Saitama Cancer Center
eDepartment of Pathology, Saitama Cardiovascular and Respiratory Center

ABSTRACT

A 67-year-old woman who had no underlying diseases developed dyspnea and fatigue 2 weeks prior to presentation at our hospital. She initially visited a local physician, who suspected congestive heart failure, and was then referred to our hospital. Thrombocytopenia, elevated serum lactate dehydrogenase, ground-glass opacities in bilateral lung fields, and hepatosplenomegaly indicated intravascular large B-cell lymphoma (IVLBCL) or pulmonary tumor embolism. Right-heart catheterization showed mild pulmonary hypertension, and pulmonary artery wedge aspiration cytology detected atypical B-cells. Random skin and bone marrow biopsies showed histological evidence compatible with IVLBCL. Chemotherapy was administered that improved her condition.

KEYWORDS

Intravascular large B-cell lymphoma(IVLBCL)  Pulmonary wedge aspiration cytology(PWAC)  Pulmonary tumor embolism(PTE)  differential diagnosis  Lung 

Received 7 Jan 2025 / Accepted 5 Feb 2025

AJRS, 14(3): 152-157, 2025

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