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Article in Japanese
Abstract
Case Report
A case of drug-induced lung injury caused by pegylated liposomal doxorubicin
Yuri Shimada Tomoyoshi Itoh Soichiro Yoshimura Fukumichi Ishiyama Tsuyoshi Hattori Yuya Inada
Department of Respiratory Medicine, Kansai Electric Power Hospital
ABSTRACT
We present a case of drug-induced lung injury caused by pegylated liposomal doxorubicin in a 49-year-old woman. Pegylated liposomal doxorubicin was administered for the first time 72 days before she was hospitalized for left fallopian tube cancer. On hospitalization, she presented with dyspnea on exertion and cough. A chest computed tomography scan revealed ground-glass opacities predominantly in both upper lung fields with consolidation, traction bronchiectasis, and interlobular septal thickening. Consequently, drug-induced lung injury caused by pegylated liposomal doxorubicin was suspected, and subsequently administered steroid therapy resulted in an improvement in computed tomography findings. Thus, physicians should consider pegylated liposomal doxorubicin as a potential cause of drug-induced lung injury.
KEYWORDS
Pegylated liposomal doxorubicin Drug-induced lung injury
Received 21 Aug 2024 ／ Accepted 14 Jan 2025
AJRS, 14(3): 141-146, 2025
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