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Article in Japanese
Abstract
Case Report
Adult T-cell leukemia/lymphoma presenting with enlarged mediastinal lymph nodes: A case report
Toshiaki Asano Mayuko Iwama Taro Tanaka Tomoko Nishio Taeko Imamura Koichiro Shima
Department of Respiratory Medicine, Nagoya Ekisaikai Hospital
ABSTRACT
We encountered an 82-year-old man who had been suffering from chest pain for two weeks before his first visit. Computed tomography revealed enlarged mediastinal lymph nodes. The soluble interleukin-2 receptor levels were elevated at 23,000U/mL, and malignant lymphoma was suspected. Endobronchial ultrasound-guided needle biopsy showed no significant findings. However, endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) revealed malignant cells, which were positive for cluster of differentiation (CD) 3 and negative for CD20 and CD79a. The patient was found to be positive for HTLV-1 antibodies and was finally diagnosed with adult T-cell leukemia/lymphoma. EBUS-IFB is useful in the diagnosis of malignant lymphoma.
KEYWORDS
Human T-cell leukemia virus type-1 (HTLV-1) Adult T-cell leukemia/lymphoma (ATLL) Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) Mediastinal lymphadenopathy
Received 11-Oct-24 ／ Accepted 22-Nov-24
AJRS, 14(2): 57-61, 2025
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