We report a case of severe drug-induced lung injury caused by an everolimus-eluting stent. A 48-year-old man presented with acute myocardial infarction to the Cardiology Department of our hospital. Everolimus-eluting coronary stents were placed in the right coronary and left circumflex coronary arteries. The patient developed pneumonia 10 days post-procedure. Chest radiography revealed bilateral lung field consolidation. Drug-induced lung injury caused by the everolimus-eluting stents was suspected. Corticosteroid therapy and recombinant thrombomodulin were administered, but response to the treatment was poor, resulting in the patient's death. Everolimus is an antineoplastic agent currently used to coat coronary stents to reduce the rates of restenosis and fatal thrombosis after coronary stent placement. Although pulmonary toxicity related to everolimus-eluting coronary stents is rare, this adverse event may occasionally be lethal. Physicians should, therefore, be aware of this potential issue.