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Article in Japanese
Abstract
Case Report
A case of drug-induced eosinophilic pneumonia caused by vedolizumab
Kei Sasaki Hibiki Kanda Yuki Imasato
Department of Respiratory Medicine, Omi Medical Center
ABSTRACT
A 46-year-old woman diagnosed with ulcerative colitis was started on mesalazine in September 20XX-1 and vedolizumab in October 20XX for induction remission therapy. She presented to our department with cough and dyspnea in December 20XX. Blood tests showed an increased eosinophil count, and chest computed tomography scan showed a pattern of dense and predominantly peripheral confluent consolidation with bronchial translucency. We suspected that she had drug-induced eosinophilic pneumonia caused by vedolizumab. We discontinued vedolizumab and started treatment with prednisolone. After the change in treatment, her pneumonia resolved promptly. We need to consider vedolizumab as a causative agent when drug-induced eosinophilic pneumonia occurs in patients being treated for ischemic bowel disease.
KEYWORDS
Drug-induced eosinophilic pneumonia Vedolizumab
Received 13 Aug 2024 ／ Accepted 11 Oct 2024
AJRS, 14(1): 39-42, 2025
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